Anti-GPI antibody [1B7D7] (STJ98114)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of human GPI expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Glucose-6-phosphate isomerase for use in WB, IHC, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1B7D7 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000IHC 1:200-1:1000IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPI |
| Gene ID | 2821 |
| Uniprot ID | G6PI_HUMAN |
| Immunogen | Purified recombinant fragment of human GPI expressed in E. Coli. |
| Specificity | GPI Monoclonal Antibody detects endogenous levels of GPI protein. |
Additional Info
| Function | In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. |
| Protein Name | Glucose-6-Phosphate IsomeraseGpiAutocrine Motility FactorAmfNeuroleukinNlkPhosphoglucose IsomerasePgiPhosphohexose IsomerasePhiSperm Antigen 36Sa-36 |
| Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-6798695Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | CytoplasmSecreted |
| Alternative Antibody Names | Anti-Glucose-6-Phosphate Isomerase antibodyAnti-Gpi antibodyAnti-Autocrine Motility Factor antibodyAnti-Amf antibodyAnti-Neuroleukin antibodyAnti-Nlk antibodyAnti-Phosphoglucose Isomerase antibodyAnti-Pgi antibodyAnti-Phosphohexose Isomerase antibodyAnti-Phi antibodyAnti-Sperm Antigen 36 antibodyAnti-Sa-36 antibodyAnti-GPI antibody |
Information sourced from Uniprot.org