| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GOT2 (30-200) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GOT2 |
| Gene ID: |
2806 |
| Uniprot ID: |
AATM_HUMAN |
| Immunogen Region: |
30-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human GOT2 (NP_002071.2). |
| Immunogen Sequence: |
SSWWTHVEMGPPDPILGVTE AFKRDTNSKKMNLGVGAYRD DNGKPYVLPSVRKAEAQIAA KNLDKEYLPIGGLAEFCKAS AELALGENSEVLKSGRFVTV QTISGTGALRIGASFLQRFF KFSRDVFLPKPTWGNHTPIF RDAGMQLQGYRYYDPKTCGF DFTGAVEDISK |
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
| Protein Name | Aspartate Aminotransferase - MitochondrialMaspatFatty Acid-Binding ProteinFabp-1Glutamate Oxaloacetate Transaminase 2Kynurenine Aminotransferase 4Kynurenine Aminotransferase IvKynurenine--Oxoglutarate Transaminase 4Kynurenine--Oxoglutarate Transaminase IvPlasma Membrane-Associated Fatty Acid-Binding ProteinFabppmTransaminase A |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-389661Reactome: R-HSA-70263Reactome: R-HSA-8963693Reactome: R-HSA-8964539 |
| Cellular Localisation | Mitochondrion MatrixCell MembraneExposure To Alcohol Promotes Translocation To The Cell Membrane |
| Alternative Antibody Names | Anti-Aspartate Aminotransferase - Mitochondrial antibodyAnti-Maspat antibodyAnti-Fatty Acid-Binding Protein antibodyAnti-Fabp-1 antibodyAnti-Glutamate Oxaloacetate Transaminase 2 antibodyAnti-Kynurenine Aminotransferase 4 antibodyAnti-Kynurenine Aminotransferase Iv antibodyAnti-Kynurenine--Oxoglutarate Transaminase 4 antibodyAnti-Kynurenine--Oxoglutarate Transaminase Iv antibodyAnti-Plasma Membrane-Associated Fatty Acid-Binding Protein antibodyAnti-Fabppm antibodyAnti-Transaminase A antibodyAnti-GOT2 antibodyAnti-KYAT4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
