Anti-GOLGA1 antibody [R04-7D1] (STJA0036476)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Golgin 97
General Information
| Short Description | Rabbit monoclonal anti-GOLGA1 for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-7D1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IP 1:30 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GOLGA1 |
| Gene ID | 2800 |
| Uniprot ID | GOGA1_HUMAN |
| Immunogen | A synthesized peptide derived from human Golgin 97 |
Additional Info
| Post Translational Modifications | MARylated by PARP12.MARylation is required for basolateral export of E-Cadherin. |
| Function | Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. Mechanistically, captures transport vesicles arriving from endosomes via the protein TBC1D23. Recognized vesicles are then tethered to the trans-Golgi before subsequent SNARE engagement and vesicle fusion. Selectively regulates E-cadherin transport from the trans-Golgi network in tubulovesicular carriers. (Microbial infection) Plays an important role in poxvirus morphogenesis. Translocates into the viral factories where it may transport the membrane fragments and associated protein factors important for virus maturation to the sites of virion assembly. |
| Protein Name | Golgin Subfamily A Member 1Golgin-97 |
| Database Links | Reactome: R-HSA-6811440 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane ProteinGolgi ApparatusTrans-Golgi Network MembraneCytoplasmic VesicleSecretory VesicleAcrosome |
| Alternative Antibody Names | Anti-Golgin Subfamily A Member 1 antibodyAnti-Golgin-97 antibodyAnti-GOLGA1 antibody |
Information sourced from Uniprot.org