Anti-GOLGA1 antibody (1-300) (STJ116890)

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STJ116890
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GOLGA1
Gene ID: 2800
Uniprot ID: GOGA1_HUMAN
Immunogen Region: 1-300
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GOLGA1 (NP_002068.1).
Immunogen Sequence: MFAKLKKKIAEETAVAQRPG GATRIPRSVSKESVASMGAD SGDDFASDGSSSREDLSSQL LRRNEQIRKLEARLSDYAEQ VRNLQKIKEKLEIALEKHQD SSMRKFQEQNETFQANRAKM AEGLALALARKDQEWSEKMD QLEKEKNILTAQLQEMKNQS MNLFQRRDEMDELEGFQQQE LSKIKHMLLKKEESLGKMEQ ELEARTRELSRTQEELMNSN QMSSDLSQKLEELQRHYST
Post Translational Modifications MARylated by PARP12.MARylation is required for basolateral export of E-Cadherin.
Function Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. Mechanistically, captures transport vesicles arriving from endosomes via the protein TBC1D23. Recognized vesicles are then tethered to the trans-Golgi before subsequent SNARE engagement and vesicle fusion. Selectively regulates E-cadherin transport from the trans-Golgi network in tubulovesicular carriers. (Microbial infection) Plays an important role in poxvirus morphogenesis. Translocates into the viral factories where it may transport the membrane fragments and associated protein factors important for virus maturation to the sites of virion assembly.
Protein Name Golgin Subfamily A Member 1
Golgin-97
Database Links Reactome: R-HSA-6811440
Cellular Localisation Golgi Apparatus Membrane
Peripheral Membrane Protein
Golgi Apparatus
Trans-Golgi Network Membrane
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome
Alternative Antibody Names Anti-Golgin Subfamily A Member 1 antibody
Anti-Golgin-97 antibody
Anti-GOLGA1 antibody

Information sourced from Uniprot.org