| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GNRHR (1-80) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GNRHR |
| Gene ID: |
2798 |
| Uniprot ID: |
GNRHR_HUMAN |
| Immunogen Region: |
1-80 |
| Immunogen: |
Recombinant fusion protein containing a sequence within amino acids 1-80 of human GNRHR (NP_000397.1). |
| Immunogen Sequence: |
MANSASPEQNQNHCSAINNS IPLMQGNLPTLTLSGKIRVT VTFFLFLLSATFNASFLLKL QKWTQKKEKGKKLSRMKLLL |
| Tissue Specificity | Pituitary, ovary, testis, breast and prostate but not in liver and spleen. |
| Function | Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling. |
| Protein Name | Gonadotropin-Releasing Hormone ReceptorGnrh ReceptorGnrh-R |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gonadotropin-Releasing Hormone Receptor antibodyAnti-Gnrh Receptor antibodyAnti-Gnrh-R antibodyAnti-GNRHR antibodyAnti-GRHR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
