• Anti-GnRH receptor antibody [F1G4] (STJ16100836)

Anti-GnRH receptor antibody [F1G4] (STJ16100836)

SKU:
STJ16100836

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Host: Mouse
Applications: ELISA/WB/IHC
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-GnRH receptor is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: F1G4
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: ELISA (solid phase: not known; tracer: 0, 001-100 µg/ml for 30 min at RT). Immunoblotting (1-2 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT; staining of formalin-fixed tissue requires boiling tissue sections in 10mM Tris with 1 mM EDTA, pH 9.0
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: GNRHR
Gene ID: 2798
Uniprot ID: GNRHR_HUMAN
Immunogen: A BALB/c mouse was immunized with a BSA-conjugated peptide corresponding to amino acids 1-29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) of human GnRH receptor extracellular domain.Fusion partner: SP2/0.
Tissue Specificity Pituitary, ovary, testis, breast and prostate but not in liver and spleen.
Function Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
Protein Name Gonadotropin-Releasing Hormone Receptor
Gnrh Receptor
Gnrh-R
Database Links Reactome: R-HSA-375281
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Gonadotropin-Releasing Hormone Receptor antibody
Anti-Gnrh Receptor antibody
Anti-Gnrh-R antibody
Anti-GNRHR antibody
Anti-GRHR antibody

Information sourced from Uniprot.org

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