| Host: |
Mouse |
| Applications: |
ELISA/WB/IHC |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-GnRH receptor is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
F1G4 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
PBS with 0.02% Sodium Azide. |
| Purification: |
Affinity purified from tissue culture. |
| Concentration: |
Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: |
ELISA (solid phase: not known; tracer: 0, 001-100 µg/ml for 30 min at RT). Immunoblotting (1-2 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT; staining of formalin-fixed tissue requires boiling tissue sections in 10mM Tris with 1 mM EDTA, pH 9.0 |
| Storage Instruction: |
Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: |
GNRHR |
| Gene ID: |
2798 |
| Uniprot ID: |
GNRHR_HUMAN |
| Immunogen: |
A BALB/c mouse was immunized with a BSA-conjugated peptide corresponding to amino acids 1-29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) of human GnRH receptor extracellular domain.Fusion partner: SP2/0. |
| Tissue Specificity | Pituitary, ovary, testis, breast and prostate but not in liver and spleen. |
| Function | Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling. |
| Protein Name | Gonadotropin-Releasing Hormone ReceptorGnrh ReceptorGnrh-R |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gonadotropin-Releasing Hormone Receptor antibodyAnti-Gnrh Receptor antibodyAnti-Gnrh-R antibodyAnti-GNRHR antibodyAnti-GRHR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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