![Anti-GnRH receptor antibody [F1G4] (STJ16100836)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149553/302399/STJ16100836_1__49598.1646940589.jpg?c=1 "Anti-GnRH receptor antibody [F1G4] (STJ16100836)")
![Anti-GnRH receptor antibody [F1G4] (STJ16100836)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149553/302399/STJ16100836_1__49598.1646940589.jpg?c=1 "Anti-GnRH receptor antibody [F1G4] (STJ16100836)")
| Host: | Mouse |
| Applications: | ELISA/WB/IHC |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-GnRH receptor is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | F1G4 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | PBS with 0.02% Sodium Azide. |
| Purification: | Affinity purified from tissue culture. |
| Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: | ELISA (solid phase: not known; tracer: 0, 001-100 µg/ml for 30 min at RT). Immunoblotting (1-2 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT; staining of formalin-fixed tissue requires boiling tissue sections in 10mM Tris with 1 mM EDTA, pH 9.0 |
| Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: | GNRHR |
| Gene ID: | 2798 |
| Uniprot ID: | GNRHR_HUMAN |
| Immunogen: | A BALB/c mouse was immunized with a BSA-conjugated peptide corresponding to amino acids 1-29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) of human GnRH receptor extracellular domain.Fusion partner: SP2/0. |
| Tissue Specificity | Pituitary, ovary, testis, breast and prostate but not in liver and spleen. |
| Function | Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling. |
| Protein Name | Gonadotropin-Releasing Hormone ReceptorGnrh ReceptorGnrh-R |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gonadotropin-Releasing Hormone Receptor antibodyAnti-Gnrh Receptor antibodyAnti-Gnrh-R antibodyAnti-GNRHR antibodyAnti-GRHR antibody |
Information sourced from Uniprot.org