Anti-GNMT antibody (1-295) (STJ28691)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GNMT (1-295) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GNMT |
| Gene ID | 27232 |
| Uniprot ID | GNMT_HUMAN |
| Immunogen Region | 1-295 |
| Immunogen Sequence | MVDSVYRTRSLGVAAEGLPD QYADGEAARVWQLYIGDTRS RTAEYKAWLLGLLRQHGCQR VLDVACGTGVDSIMLVEEGF SVTSVDASDKMLKYALKERW NRRHEPAFDKWVIEEANWMT LDKDVPQSAEGGFDAVICLG NSFAHLPDCKGDQSEHRLAL KNIASMVRAGGLLVIDHRNY DHILSTGCAPPGKNIYYKSD LTKDVTTSVLIVNNKAHMVT LDYTVQVPGAGQDGSPGLS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human GNMT (NP_061833.1). |
Additional Info
| Tissue Specificity | Expressed only in liver, pancreas, and prostate. |
| Function | Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate. Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine. |
| Protein Name | Glycine N-Methyltransferase |
| Database Links | Reactome: R-HSA-2408508Reactome: R-HSA-389661Reactome: R-HSA-9925561 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glycine N-Methyltransferase antibodyAnti-GNMT antibody |
Information sourced from Uniprot.org