Anti-GNB2 antibody [R04-1A2] (STJA0033794)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human GNB2
General Information
| Short Description | Rabbit monoclonal anti-GNB2 for use in WB, IHC-P and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-1A2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GNB2 |
| Gene ID | 2783 |
| Uniprot ID | GBB2_HUMAN |
| Immunogen | A synthetic peptide of human GNB2 |
Additional Info
| Tissue Specificity | Expressed in all cardiac subcompartments and in the brain, with highest levels in the atrioventricular node and brain. |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
| Protein Name | Guanine Nucleotide-Binding Protein G(I/G(S/G(T Subunit Beta-2G Protein Subunit Beta-2Transducin Beta Chain 2 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-163359Reactome: R-HSA-202040Reactome: R-HSA-381676Reactome: R-HSA-392170Reactome: R-HSA-392451Reactome: R-HSA-392851Reactome: R-HSA-400042Reactome: R-HSA-4086398Reactome: R-HSA-416476Reactome: R-HSA-416482Reactome: R-HSA-418217Reactome: R-HSA-418555Reactome: R-HSA-418592Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-420092Reactome: R-HSA-428930Reactome: R-HSA-432040Reactome: R-HSA-456926Reactome: R-HSA-500657Reactome: R-HSA-6814122Reactome: R-HSA-8964315Reactome: R-HSA-8964616Reactome: R-HSA-9009391Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9856530Reactome: R-HSA-997272 |
| Cellular Localisation | CytoplasmPerinuclear RegionCell Membrane |
| Alternative Antibody Names | Anti-Guanine Nucleotide-Binding Protein G(I/G(S/G(T Subunit Beta-2 antibodyAnti-G Protein Subunit Beta-2 antibodyAnti-Transducin Beta Chain 2 antibodyAnti-GNB2 antibody |
Information sourced from Uniprot.org