• Western blot analysis of lysates from LOVO cells, using GNAL Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of HEPG2-UV cells using G Alpha olf Polyclonal Antibody diluted at 1：1000
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GNAL Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using G Alpha olf Polyclonal Antibody diluted at 1：1000

Anti-GNAL antibody (41-90 aa) (STJ93458)

SKU:
STJ93458

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Guanine nucleotide-binding protein Golf subunit alpha (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GNAL
Gene ID: 2774
Uniprot ID: GNAL_HUMAN
Immunogen Region: 41-90 aa
Specificity: G Alpha olf Polyclonal Antibody detects endogenous levels of G Alpha olf protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human GNAL at the amino acid range 41-90
Function Guanine nucleotide-binding protein (G protein) involved as transducer in olfactory signal transduction controlled by G protein-coupled receptors (GPCRs). Contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. GNAL/G(olf) alpha specifically mediates olfactory signal transduction within the olfactory neuroepithelium and the basal ganglia following GPCRs activation. Acts by promoting the specific activation of adenylyl cyclase ADCY3, resulting in increased levels of the signaling molecule cAMP.
Protein Name Guanine Nucleotide-Binding Protein G(Olf Subunit Alpha
Adenylate Cyclase-Stimulating G Alpha Protein - Olfactory Type
Database Links Reactome: R-HSA-170660
Reactome: R-HSA-170670
Reactome: R-HSA-381753
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Alternative Antibody Names Anti-Guanine Nucleotide-Binding Protein G(Olf Subunit Alpha antibody
Anti-Adenylate Cyclase-Stimulating G Alpha Protein - Olfactory Type antibody
Anti-GNAL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance