| Host: | Mouse |
| Applications: | ELISA/WB/ICC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Glycine N-methyltransferase/GNMT (1-295aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | AT5D1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Purification: | By protein-A affinity chromatography |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GNMT |
| Gene ID: | 27232 |
| Uniprot ID: | GNMT_HUMAN |
| Immunogen Region: | 1-295aa |
| Accession Number: | NP_061833 |
| Immunogen: | Recombinant human GNMT (1-295aa) purified from E. coli. |
| Tissue Specificity | Expressed only in liver, pancreas, and prostate. |
| Function | Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate. Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine. |
| Protein Name | Glycine N-Methyltransferase |
| Database Links | Reactome: R-HSA-2408508Reactome: R-HSA-389661Reactome: R-HSA-9925561 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glycine N-Methyltransferase antibodyAnti-GNMT antibody |
Information sourced from Uniprot.org
