Anti-Glutathione Synthetase/GSS antibody (1-474aa) [AT12F2] (STJA0041796)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human GSS (1-474aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-Glutathione Synthetase/GSS (1-474aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT12F2 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GSS |
| Gene ID | 2937 |
| Uniprot ID | GSHB_HUMAN |
| Accession Number | NP_000169 |
| Immunogen | Recombinant human GSS (1-474aa) purified from E. coli |
| Immunogen Region | 1-474aa |
Additional Info
| Function | Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes. Participates in ophthalmate biosynthesis in hepatocytes. |
| Protein Name | Glutathione SynthetaseGsh SynthetaseGsh-SGlutathione Synthase |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-5579006 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glutathione Synthetase antibodyAnti-Gsh Synthetase antibodyAnti-Gsh-S antibodyAnti-Glutathione Synthase antibodyAnti-GSS antibody |
Information sourced from Uniprot.org