| Host: | Mouse |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Glutathione Synthetase for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 2F2 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Purification: | Affinity Purified |
| Concentration: | 0.7 mg/mL |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | GSS |
| Gene ID: | 2937 |
| Uniprot ID: | GSHB_HUMAN |
| Immunogen: | Full length human recombinant protein of human GSS produced in 293T cell. |
| Function | Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes. Participates in ophthalmate biosynthesis in hepatocytes. |
| Protein Name | Glutathione SynthetaseGsh SynthetaseGsh-SGlutathione Synthase |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-5579006 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glutathione Synthetase antibodyAnti-Gsh Synthetase antibodyAnti-Gsh-S antibodyAnti-Glutathione Synthase antibodyAnti-GSS antibody |
Information sourced from Uniprot.org
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