| Host: | Rabbit |
| Applications: | IHC-F |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Glutathione peroxidase 3 for use in IHC-F in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | Mixed |
| Purification: | Whole serum |
| Dilution Range: | IHC 1:1000-1:5000 |
| Storage Instruction: | Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at-20°C for a higher stability, and at 2-8°C with an appropriate antibacterial |
| Gene Symbol: | GPX3 |
| Gene ID: | 2878 |
| Uniprot ID: | GPX3_HUMAN |
| Specificity: | This antibody has been shown to be specific for glutathione peroxidase 3 protein (GPx-P) through staining and blocking studies. Human and rat, other species have not yet been ested. |
| Immunogen: | A synthetic peptide (FEKGDVNGEKEQKFYTFLKN) corresponding to the amino acids 135-154 of human glutathione peroxidase 3 (GPx-P) conjugated to diphtheria toxin has been used as the immunogen. The peptide is homologous with the corresponding sequence der |
| Immunogen Sequence: | Human |
| Tissue Specificity | Secreted in plasma. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. |
| Protein Name | Glutathione Peroxidase 3Gpx-3Gshpx-3Extracellular Glutathione PeroxidasePlasma Glutathione PeroxidaseGpx-PGshpx-P |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Glutathione Peroxidase 3 antibodyAnti-Gpx-3 antibodyAnti-Gshpx-3 antibodyAnti-Extracellular Glutathione Peroxidase antibodyAnti-Plasma Glutathione Peroxidase antibodyAnti-Gpx-P antibodyAnti-Gshpx-P antibodyAnti-GPX3 antibodyAnti-GPXP antibody |
Information sourced from Uniprot.org
