Anti-GLUT2 antibody (Internal) (STJ73814)

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STJ73814-100
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Short Description :Goat polyclonal antibody anti-GLUT2 (Internal) is suitable for use in ELISA, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications.
Applications:Pep-ELISA/IHC/IF/FC
Host:Goat
Reactivity:Human/Mouse/Rat/Cow/Pig
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.5 mg/mL
Purification:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range:Peptide ELISA: antibody detection limit dilution 1:8000.
IHC: In paraffin embedded Human Liver shows strong staining of the endothelial lining cells. Recommended concentration: 2-6µg/ml.
IF: Strong expression of the protein seen in the membra
Formulation:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction:Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol:SLC2A2
Gene ID:6514
Uniprot ID:GTR2_HUMAN
Accession Number:NP_000331.1
Immunogen Region:Internal
Immunogen Sequence:RKEREEASSEQKVS
Post Translational Modifications N-glycosylated.required for stability and retention at the cell surface of pancreatic beta cells.
Function Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells.may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate.
Protein Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2
Glucose Transporter Type 2 - Liver
Glut-2
Database Links Reactome: R-HSA-189200
Reactome: R-HSA-210745
Reactome: R-HSA-422356
Reactome: R-HSA-5619098
Reactome: R-HSA-8981373
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2 antibody
Anti-Glucose Transporter Type 2 - Liver antibody
Anti-Glut-2 antibody
Anti-SLC2A2 antibody
Anti-GLUT2 antibody

Information sourced from Uniprot.org