| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | GLRX5 |
| Gene ID: | 51218 |
| Uniprot ID: | GLRX5_HUMAN |
| Immunogen Region: | 32-157 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-157 of human GLRX5 (NP_057501.2). |
| Immunogen Sequence: | AGSGAGGGGSAEQLDALVKK DKVVVFLKGTPEQPQCGFSN AVVQILRLHGVRDYAAYNVL DDPELRQGIKDYSNWPTIPQ VYLNGEFVGGCDILLQMHQN GDLVEELKKLGIHSALLDEK KDQDSK |
| Function | Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1. |
| Protein Name | Glutaredoxin-Related Protein 5 - MitochondrialMonothiol Glutaredoxin-5 |
| Database Links | Reactome: R-HSA-1362409 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Glutaredoxin-Related Protein 5 - Mitochondrial antibodyAnti-Monothiol Glutaredoxin-5 antibodyAnti-GLRX5 antibodyAnti-C14orf87 antibody |
Information sourced from Uniprot.org