Anti-GLRA2 antibody (350-420) (STJ118119)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GLRA2 (350-420) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GLRA2 |
| Gene ID | 2742 |
| Uniprot ID | GLRA2_HUMAN |
| Immunogen Region | 350-420 |
| Immunogen Sequence | RLRRRQKRQNKEEDVTRESR FNFSGYGMGHCLQVKDGTAV KATPANPLPQPPKDGDAIKK KFVDRAKRIDT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of human GLRA2 (NP_002054.1). |
Additional Info
| Function | Subunit of heteromeric glycine-gated chloride channels. Plays a role in synaptic plasticity. Contributes to the generation of inhibitory postsynaptic currents, and is involved in the down-regulation of neuronal excitability. Plays a role in cellular responses to ethanol. |
| Protein Name | Glycine Receptor Subunit Alpha-2 |
| Database Links | Reactome: R-HSA-112314 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinSynapseCell MembraneCell Projection |
| Alternative Antibody Names | Anti-Glycine Receptor Subunit Alpha-2 antibodyAnti-GLRA2 antibody |
Information sourced from Uniprot.org