| Tissue Specificity | Detected in spinal cord (at protein level). Detected in spinal cord and brain stem. |
| Function | Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol. Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol. |
| Protein Name | Glycine Receptor Subunit Alpha-1Glycine Receptor 48 Kda SubunitGlycine Receptor Strychnine-Binding Subunit |
| Database Links | Reactome: R-RNO-112314 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinSynapsePerikaryonCell ProjectionDendriteCell Membrane |
| Alternative Antibody Names | Anti-Glycine Receptor Subunit Alpha-1 antibodyAnti-Glycine Receptor 48 Kda Subunit antibodyAnti-Glycine Receptor Strychnine-Binding Subunit antibodyAnti-Glra1 antibodyAnti-Glyr antibody |
Information sourced from Uniprot.org