Host: |
Goat |
Applications: |
Pep-ELISA/WB/IF/FC |
Reactivity: |
Human/Mouse/Rat/Dog/Pig/Cow |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-GLP1R (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
IF-Strong expression of the protein seen in the membranes of HeLa cells. 10µg/mlFC-Flow cytometric analysis of HeLa cells. 10ug/mlELISA-antibody detection limit dilution 1:128000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
GLP1R |
Gene ID: |
2740 |
Uniprot ID: |
GLP1R_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_002053.3 |
Specificity: |
The immunizing peptide represents part of an extracellular region. |
Immunogen Sequence: |
QHQWDGLLSYQD |
Function | G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. |
Protein Name | Glucagon-Like Peptide 1 ReceptorGlp-1 ReceptorGlp-1-RGlp-1r |
Database Links | Reactome: R-HSA-381676Reactome: R-HSA-418555Reactome: R-HSA-420092 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Glucagon-Like Peptide 1 Receptor antibodyAnti-Glp-1 Receptor antibodyAnti-Glp-1-R antibodyAnti-Glp-1r antibodyAnti-GLP1R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance