| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GLP1R (22-116) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GLP1R |
| Gene ID: |
2740 |
| Uniprot ID: |
GLP1R_HUMAN |
| Immunogen Region: |
22-116 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-116 of human GLP1R (NP_002053.3). |
| Immunogen Sequence: |
GPRPQGATVSLWETVQKWRE YRRQCQRSLTEDPPPATDLF CNRTFDEYACWPDGEPGSFV NVSCPWYLPWASSVPQGHVY RFCTAEGLWLQKDNS |
| Post Translational Modifications | N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
| Function | G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. |
| Protein Name | Glucagon-Like Peptide 1 ReceptorGlp-1 ReceptorGlp-1-RGlp-1r |
| Database Links | Reactome: R-HSA-381676Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glucagon-Like Peptide 1 Receptor antibodyAnti-Glp-1 Receptor antibodyAnti-Glp-1-R antibodyAnti-Glp-1r antibodyAnti-GLP1R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
