Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-GLIPR1-like protein 1 is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GLIPR1L1 |
Gene ID: |
256710 |
Uniprot ID: |
GPRL1_HUMAN |
Specificity: |
This antibody detects endogenous levels of GLIPR1L1 at Human |
Immunogen: |
Synthesized peptide derived from human GLIPR1L1 |
Post Translational Modifications | N-glycosylated. N-glycosylation decreases during the transit in the caput. |
Function | Required for optimal fertilization at the stage of sperm-oocyte fusion, plays a role in optimizing acrosome function, the translocation of IZUMO1 during the acrosome reaction and the fertilization process. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation. Also component of the CD9-positive microvesicules found in the cauda region. |
Protein Name | Glipr1-Like Protein 1 |
Cellular Localisation | Cytoplasmic VesicleSecretory VesicleAcrosomeCell MembraneLipid-AnchorGpi-AnchorExtracellular SideMembrane RaftSecretedLocated In The Connecting Piece Of Elongated Spermatids And SpermAlso Located In The Apical Region Of The Sperm Head After Sperm CapacitationWeakly Attached To The Cell Membrane And Later Secreted Into The Extracellular SpaceLocated On Sperm Equatorial Segment And NeckAssociated With Epididymosomes From The Caput And Cauda Epididymis |
Alternative Antibody Names | Anti-Glipr1-Like Protein 1 antibodyAnti-GLIPR1L1 antibodyAnti-UNQ2972 antibodyAnti-PRO7434 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance