| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
GK2 |
| Gene ID: |
2712 |
| Uniprot ID: |
GLPK2_HUMAN |
| Immunogen Region: |
1-150 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GK2 (NP_149991.2). |
| Immunogen Sequence: |
MAAPKTAAVGPLVGAVVQGT NSTRFLVFNSKTAELLSHHK VELTQEFPKEGWVEQDPKEI LQSVYECIARTCEKLDELNI DISNIKAVGVSNQRETTVIW DKLTGEPLYNAVVWLDLRTQ TTVEDLSKKIPGNSNFVKSK TGLPLSTYFS |
| Tissue Specificity | Testis-specific. Expressed in the midpiece of spermatozoa. |
| Function | Key enzyme in the regulation of glycerol uptake and metabolism. Essential for male fertility and sperm mitochondrial sheath formation. Required for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during spermatogenesis. Can induce mitochondrial clustering through interactions with PLD6 and up-regulation of phosphatidic acid synthesis in the mitochondria. |
| Protein Name | Glycerol Kinase 2Gk 2Glycerokinase 2Atp -Glycerol 3-Phosphotransferase 2Glycerol Kinase - Testis Specific 2 |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmIn Sperm The Majority Of The Enzyme Is Bound To Mitochondria |
| Alternative Antibody Names | Anti-Glycerol Kinase 2 antibodyAnti-Gk 2 antibodyAnti-Glycerokinase 2 antibodyAnti-Atp -Glycerol 3-Phosphotransferase 2 antibodyAnti-Glycerol Kinase - Testis Specific 2 antibodyAnti-GK2 antibodyAnti-GKP2 antibodyAnti-GKTA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
