| Tissue Specificity | Testis-specific. Expressed in the midpiece of spermatozoa. |
| Function | Key enzyme in the regulation of glycerol uptake and metabolism. Essential for male fertility and sperm mitochondrial sheath formation. Required for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during spermatogenesis. Can induce mitochondrial clustering through interactions with PLD6 and up-regulation of phosphatidic acid synthesis in the mitochondria. |
| Protein Name | Glycerol Kinase 2Gk 2Glycerokinase 2Atp -Glycerol 3-Phosphotransferase 2Glycerol Kinase - Testis Specific 2 |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmIn Sperm The Majority Of The Enzyme Is Bound To Mitochondria |
| Alternative Antibody Names | Anti-Glycerol Kinase 2 antibodyAnti-Gk 2 antibodyAnti-Glycerokinase 2 antibodyAnti-Atp -Glycerol 3-Phosphotransferase 2 antibodyAnti-Glycerol Kinase - Testis Specific 2 antibodyAnti-GK2 antibodyAnti-GKP2 antibodyAnti-GKTA antibody |
Information sourced from Uniprot.org
