Anti-GK antibody (461-510 aa) (STJ93275)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GK at the amino acid range 461-510
General Information
| Short Description | Rabbit polyclonal anti-Glycerol kinase (461-510 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GK |
| Gene ID | 2710 |
| Uniprot ID | GLPK_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GK at the amino acid range 461-510 |
| Immunogen Region | 461-510 aa |
| Specificity | GK1 Polyclonal Antibody detects endogenous levels of GK1 protein. |
Additional Info
| Function | Kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Sn-glycerol 3-phosphate is a crucial intermediate in various metabolic pathways, such as the synthesis of glycerolipids and triglycerides, glycogenesis, glycolysis and gluconeogenesis. |
| Protein Name | Glycerol KinaseGlycerokinaseAtp -Glycerol 3-Phosphotransferase |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane ProteinNucleusCytoplasmCytosolGlycerol Kinase Activity Is More Cytosolic In Some TissuesIt Probably Represents The Expression Of Isoforms Lacking A Transmembrane DomainIsoform 3: Mitochondrion Outer MembraneIn Sperm And Fetal TissuesThe Majority Of The Activity Is Associated With MitochondriaIsoform 4: CytoplasmIn Adult TissuesSuch As Liver The Glycerol Kinase Activity Is More CytosolicIt Probably Represents The Expression Of This Isoform Which Lacks A Transmembrane Domain |
| Alternative Antibody Names | Anti-Glycerol Kinase antibodyAnti-Glycerokinase antibodyAnti-Atp -Glycerol 3-Phosphotransferase antibodyAnti-GK antibody |
Information sourced from Uniprot.org