| Tissue Specificity | Isoform 2: Widely expressed in fetal and adult tissues. Isoform 3: Widely expressed in fetal and adult tissues. Isoform 4: The sole isoform expressed in adult liver and kidney. |
| Function | Kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Sn-glycerol 3-phosphate is a crucial intermediate in various metabolic pathways, such as the synthesis of glycerolipids and triglycerides, glycogenesis, glycolysis and gluconeogenesis. |
| Protein Name | Glycerol KinaseGlycerokinaseAtp -Glycerol 3-Phosphotransferase |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane ProteinNucleusCytoplasmCytosolGlycerol Kinase Activity Is More Cytosolic In Some TissuesIt Probably Represents The Expression Of Isoforms Lacking A Transmembrane DomainIsoform 3: Mitochondrion Outer MembraneIn Sperm And Fetal TissuesThe Majority Of The Activity Is Associated With MitochondriaIsoform 4: CytoplasmIn Adult TissuesSuch As Liver The Glycerol Kinase Activity Is More CytosolicIt Probably Represents The Expression Of This Isoform Which Lacks A Transmembrane Domain |
| Alternative Antibody Names | Anti-Glycerol Kinase antibodyAnti-Glycerokinase antibodyAnti-Atp -Glycerol 3-Phosphotransferase antibodyAnti-GK antibody |
Information sourced from Uniprot.org
