| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-GJA10 (Cytoplasmic Domain) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | GJA10 |
| Gene ID: | 84694 |
| Uniprot ID: | CXA10_HUMAN |
| Immunogen Region: | Cytoplasmic Domain |
| Specificity: | Specific for Connexin-62. |
| Immunogen: | A synthetic peptide from 3d cytoplasmic domain of human Connexin-62 (CX62, Gap junction alpha-10 protein) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning. |
| Protein Name | Gap Junction Alpha-10 Protein Connexin-62 Cx62 |
| Database Links | Reactome: R-HSA-112303 Reactome: R-HSA-190861 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cell Junction Gap Junction |
| Alternative Antibody Names | Anti-Gap Junction Alpha-10 Protein antibody Anti-Connexin-62 antibody Anti-Cx62 antibody Anti-GJA10 antibody Anti-CX62 antibody |
Information sourced from Uniprot.org