Anti-GIRK2/KCNJ6 antibody (C-Term) (STJ71310)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GIRK2/KCNJ6 (C-Term) is suitable for use in ELISA, Western Blot and Immunocytochemistry research applications. |
| Applications | Pep-ELISA/WB/ICC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 48kDa band observed in Human Brain (Hippocampus and Substantia Nigra) lysates (calculated MW of 48.5kDa according to NP_002231.1). Recommended concentration: 2-6µg/ml. Primary i |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | KCNJ6 |
| Gene ID | 3763 |
| Uniprot ID | KCNJ6_HUMAN |
| Accession Number | NP_002231.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | SSKLNQHAELET |
Additional Info
| Function | This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. |
| Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 2Girk-2Bir1Inward Rectifier K(+ Channel Kir3.2Katp-2Potassium Channel - Inwardly Rectifying Subfamily J Member 6 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G Protein-Activated Inward Rectifier Potassium Channel 2 antibodyAnti-Girk-2 antibodyAnti-Bir1 antibodyAnti-Inward Rectifier K(+ Channel Kir3.2 antibodyAnti-Katp-2 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 6 antibodyAnti-KCNJ6 antibodyAnti-GIRK2 antibodyAnti-KATP2 antibodyAnti-KCNJ7 antibody |
Information sourced from Uniprot.org