| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GIPR |
| Gene ID: | 2696 |
| Uniprot ID: | GIPR_HUMAN |
| Immunogen Region: | 22-138 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-138 of human GIPR (NP_000155.1). |
| Immunogen Sequence: | RAETGSKGQTAGELYQRWER YRRECQETLAAAEPPSGLAC NGSFDMYVCWDYAAPNATAR ASCPWYLPWHHHVAAGFVLR QCGSDGQWGLWRDHTQCENP EKNEAFLDQRLILERLQ |
| Post Translational Modifications | N-glycosylation is required for cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
| Function | This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Protein Name | Gastric Inhibitory Polypeptide ReceptorGip-RGlucose-Dependent Insulinotropic Polypeptide Receptor |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gastric Inhibitory Polypeptide Receptor antibodyAnti-Gip-R antibodyAnti-Glucose-Dependent Insulinotropic Polypeptide Receptor antibodyAnti-GIPR antibody |
Information sourced from Uniprot.org