| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GHRHR |
| Gene ID: | 2692 |
| Uniprot ID: | GHRHR_HUMAN |
| Immunogen Region: | 1-130 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GHRHR (NP_000814.2). |
| Immunogen Sequence: | MDRRMWGAHVFCVLSPLPTV LGHMHPECDFITQLREDESA CLQAAEEMPNTTLGCPATWD GLLCWPTAGSGEWVTLPCPD FFSHFSSESGAVKRDCTITG WSEPFPPYPVACPVPLELLA EEESYFSTVK |
| Tissue Specificity | Pituitary gland. |
| Function | Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. |
| Protein Name | Growth Hormone-Releasing Hormone ReceptorGhrh ReceptorGrowth Hormone-Releasing Factor ReceptorGrf ReceptorGrfr |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Growth Hormone-Releasing Hormone Receptor antibodyAnti-Ghrh Receptor antibodyAnti-Growth Hormone-Releasing Factor Receptor antibodyAnti-Grf Receptor antibodyAnti-Grfr antibodyAnti-GHRHR antibody |
Information sourced from Uniprot.org