| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Ghrelin O-acyltransferase (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Preliminary experiments in Human Duodenum, Ileum and Pancreas lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedba |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MBOAT4 |
| Gene ID: | 619373 |
| Uniprot ID: | MBOA4_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001094386.1 |
| Immunogen Sequence: | QSPGEEGYVPDAD |
| Post Translational Modifications | Not glycosylated. |
| Function | Catalyzes ghrelin acylation at 'Ser-3' using preferentially octanoyl-CoA, hexanoyl-CoA and decanoyl-CoA as acyl-CoA donors leading to ghrelin activity. In vitro uses also acyl-CoA donors of different lengths from short-chain (C2) to long-chain fatty acids (C16) knowing that acyl-CoA donors from butanoyl-CoA (C4) to dodecanoyl-CoA (C12) are more efficient compared to longer acyl-CoA donors, such as myristoyl-CoA (C14) and palmitoyl-CoA (C16) that are not efficient. |
| Protein Name | Ghrelin O-AcyltransferaseMembrane-Bound O-Acyltransferase Domain-Containing Protein 4O-Acyltransferase Domain-Containing Protein 4 |
| Database Links | Reactome: R-HSA-422085 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ghrelin O-Acyltransferase antibodyAnti-Membrane-Bound O-Acyltransferase Domain-Containing Protein 4 antibodyAnti-O-Acyltransferase Domain-Containing Protein 4 antibodyAnti-MBOAT4 antibodyAnti-GOAT antibodyAnti-OACT4 antibodyAnti-FKSG89 antibody |
Information sourced from Uniprot.org