Host: | Rabbit |
Applications: | ELISA/IHC/IP/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-GGCX (400-450) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
Purification: | Affinity Purified |
Concentration: | 0.55-0.75 µg/µl |
Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150IHC: 1:50-1:100 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | GGCX |
Gene ID: | 2677 |
Uniprot ID: | VKGC_HUMAN |
Immunogen Region: | 400-450 |
Immunogen: | Synthetic peptide taken within amino acid region 400-450 on human GGCX protein. |
Function | Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. Catalyzes gamma-carboxylation of various proteins, such as blood coagulation factors (F2, F7, F9 and F10), osteocalcin (BGLAP) or matrix Gla protein (MGP). |
Protein Name | Vitamin K-Dependent Gamma-CarboxylaseGamma-Glutamyl CarboxylasePeptidyl-Glutamate 4-CarboxylaseVitamin K Gamma Glutamyl Carboxylase |
Database Links | Reactome: R-HSA-159740Reactome: R-HSA-9673240 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Vitamin K-Dependent Gamma-Carboxylase antibodyAnti-Gamma-Glutamyl Carboxylase antibodyAnti-Peptidyl-Glutamate 4-Carboxylase antibodyAnti-Vitamin K Gamma Glutamyl Carboxylase antibodyAnti-GGCX antibodyAnti-GC antibody |
Information sourced from Uniprot.org