| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GGCT |
| Gene ID: | 79017 |
| Uniprot ID: | GGCT_HUMAN |
| Immunogen Region: | 1-188 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-188 of human GGCT (NP_076956.1). |
| Immunogen Sequence: | MANSGCKDVTGPDEESFLYF AYGSNLLTERIHLRNPSAAF FCVARLQDFKLDFGNSQGKT SQTWHGGIATIFQSPGDEVW GVVWKMNKSNLNSLDEQEGV KSGMYVVIEVKVATQEGKEI TCRSYLMTNYESAPPSPQYK KIICMGAKENGLPLEYQEKL KAIEPNDYTGKVSEEIEDII KKGETQTL |
| Function | Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. |
| Protein Name | Gamma-GlutamylcyclotransferaseCytochrome C-Releasing Factor 21 |
| Database Links | Reactome: R-HSA-174403 |
| Alternative Antibody Names | Anti-Gamma-Glutamylcyclotransferase antibodyAnti-Cytochrome C-Releasing Factor 21 antibodyAnti-GGCT antibodyAnti-C7orf24 antibodyAnti-CRF21 antibody |
Information sourced from Uniprot.org