Anti-GGA2 antibody (STJA0007744)

SKU:
STJA0007744
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-ADP-ribosylation factor-binding protein GGA2 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GGA2
Gene ID: 23062
Uniprot ID: GGA2_HUMAN
Specificity: This antibody detects endogenous levels of GGA2 at Human, Mouse
Immunogen: Synthesized peptide derived from human GGA2
Post Translational Modifications Ubiquitinated.
Function Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network.
Protein Name Adp-Ribosylation Factor-Binding Protein Gga2
Gamma-Adaptin-Related Protein 2
Golgi-Localized - Gamma Ear-Containing - Arf-Binding Protein 2
Vhs Domain And Ear Domain Of Gamma-Adaptin
Vear
Database Links Reactome: R-HSA-8854214
Reactome: R-HSA-977225
Cellular Localisation Golgi Apparatus
Trans-Golgi Network Membrane
Peripheral Membrane Protein
Endosome Membrane
Early Endosome Membrane
Alternative Antibody Names Anti-Adp-Ribosylation Factor-Binding Protein Gga2 antibody
Anti-Gamma-Adaptin-Related Protein 2 antibody
Anti-Golgi-Localized - Gamma Ear-Containing - Arf-Binding Protein 2 antibody
Anti-Vhs Domain And Ear Domain Of Gamma-Adaptin antibody
Anti-Vear antibody
Anti-GGA2 antibody
Anti-KIAA1080 antibody

Information sourced from Uniprot.org

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