Anti-GFRA4 antibody [SAA1900] (STJA0020328)

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STJA0020328
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Gdnf Family Receptor Alpha-4 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1900
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: GFRA4
Gene ID: 64096
Uniprot ID: GFRA4_HUMAN
Function Receptor for persephin (PSPN), a growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons. Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Protein Name Gdnf Family Receptor Alpha-4
Gdnf Receptor Alpha-4
Gdnfr-Alpha-4
Gfr-Alpha-4
Persephin Receptor
Database Links Reactome: R-HSA-419037
Reactome: R-HSA-5673001
Reactome: R-HSA-8853659
Cellular Localisation Isoform Gfralpha4a: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform Gfralpha4b: Cell Membrane
Isoform Gfralpha4c: Secreted
Alternative Antibody Names Anti-Gdnf Family Receptor Alpha-4 antibody
Anti-Gdnf Receptor Alpha-4 antibody
Anti-Gdnfr-Alpha-4 antibody
Anti-Gfr-Alpha-4 antibody
Anti-Persephin Receptor antibody
Anti-GFRA4 antibody

Information sourced from Uniprot.org

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