Anti-GFRA3 antibody [SAA0178] {PE} (STJA0030840)
SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationPE
IsotypeIgG4k
General Information
| Short Description | Human monoclonal Gdnf Family Receptor Alpha-3 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Human |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0178 |
| Isotype | IgG4k |
| Conjugation | PE |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | GFRA3 |
| Gene ID | 2676 |
| Uniprot ID | GFRA3_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons. ARTN-binding leads to autophosphorylation and activation of the RET receptor. |
| Protein Name | Gdnf Family Receptor Alpha-3Gdnf Receptor Alpha-3Gdnfr-Alpha-3Gfr-Alpha-3 |
| Database Links | Reactome: R-HSA-5673001Reactome: R-HSA-8853659 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Gdnf Family Receptor Alpha-3 antibodyAnti-Gdnf Receptor Alpha-3 antibodyAnti-Gdnfr-Alpha-3 antibodyAnti-Gfr-Alpha-3 antibodyAnti-GFRA3 antibodyAnti-UNQ339 antibodyAnti-PRO538 antibodyAnti-PRO3664 antibody |
Information sourced from Uniprot.org