Anti-GFRA2 antibody (320-400 aa) (STJ192348)

SKU:
STJ192348
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-GDNF family receptor alpha-2 (320-400 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
ELISA 1:5000-20000
Formulation:Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:GFRA2
Gene ID:2675
Uniprot ID:GFRA2_HUMAN
Immunogen:Synthesized peptide derived from the human protein at the amino acid range 320-400
Immunogen Region:320-400 aa
Specificity:GFRA2 Polyclonal Antibody detects endogenous levels of protein.
Function Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons. NRTN-binding leads to autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. Isoform 2: Participates in NRTN-induced 'Ser-727' phosphorylation of STAT3.
Protein Name Gdnf Family Receptor Alpha-2
Gdnf Receptor Alpha-2
Gdnfr-Alpha-2
Gfr-Alpha-2
Gdnf Receptor Beta
Gdnfr-Beta
Neurturin Receptor Alpha
Nrtnr-Alpha
Ntnr-Alpha
Ret Ligand 2
Tgf-Beta-Related Neurotrophic Factor Receptor 2
Database Links Reactome: R-HSA-419037
Reactome: R-HSA-5673001
Reactome: R-HSA-8853659
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Gdnf Family Receptor Alpha-2 antibody
Anti-Gdnf Receptor Alpha-2 antibody
Anti-Gdnfr-Alpha-2 antibody
Anti-Gfr-Alpha-2 antibody
Anti-Gdnf Receptor Beta antibody
Anti-Gdnfr-Beta antibody
Anti-Neurturin Receptor Alpha antibody
Anti-Nrtnr-Alpha antibody
Anti-Ntnr-Alpha antibody
Anti-Ret Ligand 2 antibody
Anti-Tgf-Beta-Related Neurotrophic Factor Receptor 2 antibody
Anti-GFRA2 antibody
Anti-GDNFRB antibody
Anti-RETL2 antibody
Anti-TRNR2 antibody

Information sourced from Uniprot.org

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