| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GFM1 |
| Gene ID: | 85476 |
| Uniprot ID: | EFGM_HUMAN |
| Immunogen Region: | 482-751 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 482-751 of human GFM1 (NP_079272.4). |
| Immunogen Sequence: | VYFDTENKETVISGMGELHL EIYAQRLEREYGCPCITGKP KVAFRETITAPVPFDFTHKK QSGGAGQYGKVIGVLEPLDP EDYTKLEFSDETFGSNIPKQ FVPAVEKGFLDACEKGPLSG HKLSGLRFVLQDGAHHMVDS NEISFIRAGEGALKQALANA TLCILEPIMAVEVVAPNEFQ GQVIAGINRRHGVITGQDGV EDYFTLYADVPLNDMFGYST ELRSCTEGKGEYTMEYSRY |
| Function | Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. |
| Protein Name | Elongation Factor G - MitochondrialEf-GmtElongation Factor G 1 - MitochondrialMef-G 1Elongation Factor G1Hefg1 |
| Database Links | Reactome: R-HSA-5389840 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Elongation Factor G - Mitochondrial antibodyAnti-Ef-Gmt antibodyAnti-Elongation Factor G 1 - Mitochondrial antibodyAnti-Mef-G 1 antibodyAnti-Elongation Factor G1 antibodyAnti-Hefg1 antibodyAnti-GFM1 antibodyAnti-EFG antibodyAnti-EFG1 antibodyAnti-GFM antibody |
Information sourced from Uniprot.org