| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-GEM (34-46) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: In transfected HEK293 transiently expressing Human recombinant GEM bands of approx. 35+45kDa are observed. These bands are not observed in the transfected HEK293 with empty vector and |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GEM |
| Gene ID: | 2669 |
| Uniprot ID: | GEM_HUMAN |
| Immunogen Region: | 34-46 |
| Accession Number: | NP_005252.1 |
| Specificity: | Reported variants represent identical protein: NP_005252.1, NP_859053.1 |
| Immunogen Sequence: | QKEPHQYSHRNRH |
| Post Translational Modifications | Phosphorylated on tyrosine residues. |
| Function | Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. |
| Protein Name | Gtp-Binding Protein GemGtp-Binding Mitogen-Induced T-Cell ProteinRas-Like Protein Kir |
| Database Links | Reactome: R-HSA-9768919 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Gtp-Binding Protein Gem antibodyAnti-Gtp-Binding Mitogen-Induced T-Cell Protein antibodyAnti-Ras-Like Protein Kir antibodyAnti-GEM antibodyAnti-KIR antibody |
Information sourced from Uniprot.org