| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Rab GDP dissociation inhibitor beta (C-Term) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GDI2 |
| Gene ID: | 2665 |
| Uniprot ID: | GDIB_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | GDI-2 Polyclonal Antibody detects endogenous levels of GDI-2 protein. |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human GDI-2. |
| Function | GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking. Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A. |
| Protein Name | Rab Gdp Dissociation Inhibitor BetaRab Gdi BetaGuanosine Diphosphate Dissociation Inhibitor 2Gdi-2 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Rab Gdp Dissociation Inhibitor Beta antibodyAnti-Rab Gdi Beta antibodyAnti-Guanosine Diphosphate Dissociation Inhibitor 2 antibodyAnti-Gdi-2 antibodyAnti-GDI2 antibodyAnti-RABGDIB antibody |
Information sourced from Uniprot.org