Anti-GDF3 antibody [R09-3A8] (STJA0036944)

SKU:
STJA0036944
£133.50 - £281.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-GDF3 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R09-3A8
Conjugation: Unconjugated
Isotype: IgG
Formulation: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Chromatography
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: GDF3
Gene ID: 9573
Uniprot ID: GDF3_HUMAN
Immunogen: A synthesized peptide derived from human GDF3
Post Translational Modifications Synthesized as large precursor molecule that undergo proteolytic cleavage, releasing the pro-domain from the active, receptor binding, C-terminal region of the molecule.
Function Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO. Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto.
Protein Name Growth/Differentiation Factor 3
Gdf-3
Database Links
Cellular Localisation Secreted
Cytoplasm
Mainly Accumulated In The Cytoplasm
Alternative Antibody Names Anti-Growth/Differentiation Factor 3 antibody
Anti-Gdf-3 antibody
Anti-GDF3 antibody
Anti-UNQ222 antibody
Anti-PRO248 antibody

Information sourced from Uniprot.org

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