Anti-GDF3 antibody (311-360 aa) (STJ97341)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Growth/differentiation factor 3 at the amino acid range 311-360
General Information
| Short Description | Rabbit polyclonal anti-Growth/differentiation factor 3 (311-360 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GDF3 |
| Gene ID | 9573 |
| Uniprot ID | GDF3_HUMAN |
| Immunogen | Synthesized peptide derived from Growth/differentiation factor 3 at the amino acid range 311-360 |
| Immunogen Region | 311-360 aa |
| Specificity | GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein. |
Additional Info
| Function | Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO. Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto. |
| Protein Name | Growth/Differentiation Factor 3Gdf-3 |
| Database Links | |
| Cellular Localisation | SecretedCytoplasmMainly Accumulated In The Cytoplasm |
| Alternative Antibody Names | Anti-Growth/Differentiation Factor 3 antibodyAnti-Gdf-3 antibodyAnti-GDF3 antibodyAnti-UNQ222 antibodyAnti-PRO248 antibody |
Information sourced from Uniprot.org