Host: | Mouse |
Applications: | ELISA/FC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Growth/Differentiation Factor 2 is suitable for use in ELISA and Flow Cytometry research applications. |
Clonality : | Monoclonal |
Clone ID : | SAA0427 |
Conjugation: | Unconjugated |
Isotype: | IgG2ak |
Formulation: | 0.01M PBS, pH 7.4, 0.09% Sodium azide. |
Purification: | Protein A/G purified from cell culture supernatant. |
Concentration: | 1 mg/ml |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | GDF2 |
Gene ID: | 2658 |
Uniprot ID: | GDF2_HUMAN |
Post Translational Modifications | A reversible disulfide bond can be formed between the two subunits in the homodimer.this has no effect on GDF2 activity. |
Function | Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. |
Protein Name | Growth/Differentiation Factor 2Gdf-2Bone Morphogenetic Protein 9Bmp-9 |
Database Links | Reactome: R-HSA-201451 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Growth/Differentiation Factor 2 antibodyAnti-Gdf-2 antibodyAnti-Bone Morphogenetic Protein 9 antibodyAnti-Bmp-9 antibodyAnti-GDF2 antibodyAnti-BMP9 antibody |
Information sourced from Uniprot.org