Anti-GCNT3 antibody (27-180) (STJ115175)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GCNT3 (27-180) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GCNT3 |
| Gene ID | 9245 |
| Uniprot ID | GCNT3_HUMAN |
| Immunogen Region | 27-180 |
| Immunogen Sequence | LKLSFRLKCDSDHLGLESRE SQSQYCRNILYNFLKLPAKR SINCSGVTRGDQEAVLQAIL NNLEVKKKREPFTDTHYLSL TRDCEHFKAERKFIQFPLSK EEVEFPIAYSMVIHEKIENF ERLLRAVYAPQNIYCVHVDE KSPETFKEAVKAII |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 27-180 of human GCNT3 (NP_004742.1). |
Additional Info
| Tissue Specificity | Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced. |
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Also has I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
| Protein Name | Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 C2gnt-Mucin TypeC2gnt-MHc2gnt-MCore 2/Core 4 Beta-1 -6-N-AcetylglucosaminyltransferaseC2/4gnt |
| Database Links | Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 antibodyAnti-C2gnt-Mucin Type antibodyAnti-C2gnt-M antibodyAnti-Hc2gnt-M antibodyAnti-Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase antibodyAnti-C2/4gnt antibodyAnti-GCNT3 antibody |
Information sourced from Uniprot.org