| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GCNT3 (27-180) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GCNT3 |
| Gene ID: |
9245 |
| Uniprot ID: |
GCNT3_HUMAN |
| Immunogen Region: |
27-180 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 27-180 of human GCNT3 (NP_004742.1). |
| Immunogen Sequence: |
LKLSFRLKCDSDHLGLESRE SQSQYCRNILYNFLKLPAKR SINCSGVTRGDQEAVLQAIL NNLEVKKKREPFTDTHYLSL TRDCEHFKAERKFIQFPLSK EEVEFPIAYSMVIHEKIENF ERLLRAVYAPQNIYCVHVDE KSPETFKEAVKAII |
| Tissue Specificity | Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced. |
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
| Protein Name | Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 C2gnt-Mucin TypeC2gnt-MHc2gnt-MCore 2/Core 4 Beta-1 -6-N-AcetylglucosaminyltransferaseC2/4gnt |
| Database Links | Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 antibodyAnti-C2gnt-Mucin Type antibodyAnti-C2gnt-M antibodyAnti-Hc2gnt-M antibodyAnti-Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase antibodyAnti-C2/4gnt antibodyAnti-GCNT3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
