| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 3 (226-275 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GCNT3 |
| Gene ID: | 9245 |
| Uniprot ID: | GCNT3_HUMAN |
| Immunogen Region: | 226-275 aa |
| Specificity: | GCNT3 Polyclonal Antibody detects endogenous levels of GCNT3 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GCNT3 at the amino acid range 226-275 |
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
| Protein Name | Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 C2gnt-Mucin TypeC2gnt-MHc2gnt-MCore 2/Core 4 Beta-1 -6-N-AcetylglucosaminyltransferaseC2/4gnt |
| Database Links | Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 antibodyAnti-C2gnt-Mucin Type antibodyAnti-C2gnt-M antibodyAnti-Hc2gnt-M antibodyAnti-Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase antibodyAnti-C2/4gnt antibodyAnti-GCNT3 antibody |
Information sourced from Uniprot.org