| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Glycine amidinotransferase, mitochondrial (223-273 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GATM |
| Gene ID: |
2628 |
| Uniprot ID: |
GATM_HUMAN |
| Immunogen Region: |
223-273 aa |
| Specificity: |
This antibody detects endogenous levels of GATM at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human GATM at the amino acid range 223-273 |
| Function | Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain (Probable). |
| Protein Name | Glycine Amidinotransferase - MitochondrialL-Arginine -Glycine AmidinotransferaseTransamidinase |
| Database Links | Reactome: R-HSA-71288 |
| Cellular Localisation | Isoform 1: Mitochondrion Inner MembranePeripheral Membrane ProteinIntermembrane SideProbably Attached To The Outer Side Of The Inner MembraneIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Glycine Amidinotransferase - Mitochondrial antibodyAnti-L-Arginine -Glycine Amidinotransferase antibodyAnti-Transamidinase antibodyAnti-GATM antibodyAnti-AGAT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
