Anti-GATA3 antibody [SAA0103] {PerCP} (STJA0030277)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationPerCP
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal Trans-Acting T-Cell-Specific Transcription Factor Gata-3 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0103 |
| Isotype | IgG1k |
| Conjugation | PerCP |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | GATA3 |
| Gene ID | 2625 |
| Uniprot ID | GATA3_HUMAN |
Additional Info
| Function | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages. |
| Protein Name | Trans-Acting T-Cell-Specific Transcription Factor Gata-3Gata-Binding Factor 3 |
| Database Links | Reactome: R-HSA-5689880Reactome: R-HSA-6785807Reactome: R-HSA-8939236Reactome: R-HSA-9018519Reactome: R-HSA-9830364Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Trans-Acting T-Cell-Specific Transcription Factor Gata-3 antibodyAnti-Gata-Binding Factor 3 antibodyAnti-GATA3 antibody |
Information sourced from Uniprot.org