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Anti-GATA3 antibody (Full length) [ZR358] (STJ180513)

Formalin-fixed, paraffin-embedded human breast ductal carcinoma stained with anti-GATA3 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of tumor cells

Anti-GATA3 antibody (Full length) [ZR358] (STJ180513)

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STJ180513

$218.03 - $843.08

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	IHC-P
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-GATA3 (Full length) is suitable for use in Immunohistochemistry research applications.

Clonality:	Monoclonal
Clone ID:	ZR358
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification:	Affinity purified
Dilution Range:	1:100-200
Storage Instruction:	Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.

Gene Symbol:	GATA3
Gene ID:	2625
Uniprot ID:	GATA3_HUMAN
Immunogen Region:	Full length
Specificity:	Positive control: Breast or urothelial carcinoma
Immunogen:	Full-length human GATA-3 protein

Tissue Specificity	T-cells and endothelial cells.
Function	Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages.
Protein Name	Trans-Acting T-Cell-Specific Transcription Factor Gata-3 Gata-Binding Factor 3
Database Links	Reactome: R-HSA-5689880 Reactome: R-HSA-6785807 Reactome: R-HSA-8939236 Reactome: R-HSA-9018519 Reactome: R-HSA-983231
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Trans-Acting T-Cell-Specific Transcription Factor Gata-3 antibody Anti-Gata-Binding Factor 3 antibody Anti-GATA3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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