Anti-GAS2 antibody (STJ190841)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Growth arrest-specific protein 2 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GAS2 |
| Gene ID | 2620 |
| Uniprot ID | GAS2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | GAS2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Cleaved, during apoptosis, on a specific aspartic residue by caspases. Phosphorylated on serine residues during the G0-G1 transition phase. |
| Function | Required to maintain microtubule bundles in inner ear supporting cells, affording them with mechanical stiffness to transmit sound energy through the cochlea. |
| Protein Name | Growth Arrest-Specific Protein 2Gas-2 |
| Database Links | Reactome: R-HSA-264870 |
| Cellular Localisation | CytoplasmCytoskeletonStress FiberMembranePeripheral Membrane ProteinComponent Of The Microfilament SystemColocalizes With Actin Fibers At The Cell Border And Along The Stress Fibers In Growth-Arrested FibroblastsMainly Membrane-AssociatedWhen HyperphosphorylatedAccumulates At Membrane RufflesColocalizes With Detyrosinated Alpha-Tubulin Along The Length Of Microtubule Bundles In Inner And Outer Pillar Cells |
| Alternative Antibody Names | Anti-Growth Arrest-Specific Protein 2 antibodyAnti-Gas-2 antibodyAnti-GAS2 antibody |
Information sourced from Uniprot.org