Anti-Gamma-Tubulin antibody [SRM] (STJ11106968)

SKU:
STJ11106968

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Monoclonal
Clone ID: SRM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: TUBG1
Gene ID: 7283
Uniprot ID: TBG1_HUMAN
Specificity: Recombinant protein of human Gamma-Tubulin.
Immunogen Sequence: LVSTIMSASTTTLRYPGYMN NDLIGLIASLIPTPRLHFLM TGYTPLTTDQSVASVRKTTV LDVMRRLLQPKNVMVSTGRD RQTNHCYIAILNIIQGEVDP TQVHKSLQRIRERKLANFIP WGPASIQVALSRKSPYLPSA HRVSGLMMANHTSISSLFER TCRQYDKLRKREAFLEQFRK EDMFKDNFDEMDTSREIVQQ LIDEYHAATRPDYISWGTQE Q
Post Translational Modifications Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome.
Function Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
Protein Name Tubulin Gamma-1 Chain
Gamma-1-Tubulin
Gamma-Tubulin Complex Component 1
Gcp-1
Database Links Reactome: R-HSA-2565942
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-5620912
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle
Localizes To Mitotic Spindle Microtubules
Alternative Antibody Names Anti-Tubulin Gamma-1 Chain antibody
Anti-Gamma-1-Tubulin antibody
Anti-Gamma-Tubulin Complex Component 1 antibody
Anti-Gcp-1 antibody
Anti-TUBG1 antibody
Anti-TUBG antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance