| Short Description : | Rabbit polyclonal GADD45A (1-165) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GADD45A |
| Gene ID: | 1647 |
| Uniprot ID: | GA45A_HUMAN |
| Immunogen Region: | 1-165 |
| Immunogen Sequence: | MTLEEFSAGEQKTERMDKVG DALEEVLSKALSQRTITVGV YEAAKLLNVDPDNVVLCLLA ADEDDDRDVALQIHFTLIQA FCCENDINILRVSNPGRLAE LLLLETDAGPAASEGAEQPP DLHCVLVTNPHSSQWKDPAL SQLICFCRESRYMDQWVPVI NLPER |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human GADD45A (NP_001915.1). |
| Function | In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes.stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. |
| Protein Name | Growth Arrest And Dna Damage-Inducible Protein Gadd45 AlphaDna Damage-Inducible Transcript 1 ProteinDdit-1 |
| Database Links | Reactome: R-HSA-6804114Reactome: R-HSA-9617828 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Growth Arrest And Dna Damage-Inducible Protein Gadd45 Alpha antibodyAnti-Dna Damage-Inducible Transcript 1 Protein antibodyAnti-Ddit-1 antibodyAnti-GADD45A antibodyAnti-DDIT1 antibodyAnti-GADD45 antibody |
Information sourced from Uniprot.org
