Anti-GABRQ antibody (317-367 aa) (STJ193914)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human GBRT at the amino acid range 317-367
General Information
| Short Description | Rabbit polyclonal anti-Gamma-aminobutyric acid receptor subunit theta receptor subunit theta (317-367 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GABRQ |
| Gene ID | 55879 |
| Uniprot ID | GBRT_HUMAN |
| Immunogen | Synthesized peptide derived from the human GBRT at the amino acid range 317-367 |
| Immunogen Region | 317-367 aa |
| Specificity | This antibody detects endogenous levels of GBRT at Human/Mouse |
Additional Info
| Function | Theta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interfaces. When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient. |
| Protein Name | Gamma-Aminobutyric Acid Receptor Subunit ThetaGaba(A Receptor Subunit ThetaGabaar Subunit Theta |
| Database Links | Reactome: R-HSA-1236394Reactome: R-HSA-977443 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Gamma-Aminobutyric Acid Receptor Subunit Theta antibodyAnti-Gaba(A Receptor Subunit Theta antibodyAnti-Gabaar Subunit Theta antibodyAnti-GABRQ antibody |
Information sourced from Uniprot.org